DREADD agonist 21
DREADD agonist 21 is a highly potent and selective activator of engineered human M3 muscarinic receptors (hM3Dq), with an EC50 of 1.7 nM. It is a key research chemical for precise neuronal manipulation in chemogenetics, enabling the targeted control of specific cell populations in both in vitro cellular assays and in vivo animal models of neuroscience.
Product Specifications
CAS Number
56296-18-5
Product Name Alternative
Disease, DREADD, DREADD agonist 21, DREADD agonist21, DREADD agonist-21, 5-HT2A, 5HT2A serotonin receptor 5HT2A, 5-HT2C, 5HT2C serotonin receptor, acetylcholine, Adrenergic Receptor, AdrenergicReceptor, activation, 5HTReceptor, 5HT Receptor, H1 receptor, H1 histamine receptor, Inhibitor, hM3Dq, hM4, hM4Di, hM1, hM1Dq, HistamineReceptor, Histamine Receptor, inhibit, muscarinic, Muscarinic acetylcholine receptor, M4 mAChR, M1 mAChR, mAChR, neuronal, neurodegenerative, receptors, schizophrenia, α1A-adrenergic receptor, α1A adrenergic receptor
Field of Research
Immunology & Inflammation, Neuroscience, Pharmacology & Drug Discovery
Purity
98.27% (May vary between batches)
Solubility
DMSO:75 mg/mL (269.44 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (7.19 mM)
Smiles
C1CN (CCN1) C1=Nc2ccccc2Nc2ccccc12
Molecular Formula
C17H18N4
Molecular Weight
278.35
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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