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ML-180

ML-180 (SR1848) is a potent small molecule inverse agonist of the orphan nuclear receptor LRH-1 (NR5A2), exhibiting an IC50 of 3.7 μM. This compound is a valuable research tool for studying LRH-1's role in metabolism, inflammation, and cancer in both cellular and animal models.

Product Specifications

CAS Number

863588-32-3

Product Name Alternative

Cancers, factor-1, Inhibitor, homolog, inhibit, NR5A2, NR5A1, liver, nuclear, Orphan, orphan nuclear receptor NR5A2, LRH-1, ML180, ML-180, ML 180, SF-1, receptor, SR1848, SR-1848, SR 1848, steroidogenic

Field of Research

Pharmacology & Drug Discovery

Purity

99.74% (May vary between batches)

Solubility

DMSO:11 mg/mL (28.29 mM)

Smiles

Clc1cccc (c1) N1CCN (CC1) c1cc (=O) n (C2CCCCC2) c (=O) [nH]1

Molecular Formula

C20H25ClN4O2

Molecular Weight

388.89

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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