Nevanimibe hydrochloride
Nevanimibe hydrochloride (PD-132301 hydrochloride) is a potent and selective ACAT1 inhibitor with an EC50 of 9 nM, suitable for oral administration. This small molecule is a valuable research tool for investigating cholesterol metabolism and atherosclerosis in both cellular and animal models.
Product Specifications
CAS Number
133825-81-7
Product Name Alternative
Mono- acylglycerol acyltransferase, Inhibitor, inhibit, PD132301, PD-132301, PD132301 Hydrochloride, PD-132301 Hydrochloride, PD-132301 hydrochloride, PD 132301, PD 132301 Hydrochloride, Nevanimibe, Nevanimibe hydrochloride, Nevanimibe Hydrochloride, orally, O-acyltransferase, acyl-coenzyme, acyl-CoA:cholesterol acyltransferase, Acyltransferase, ACAT-1, A:cholesterol, adrenocortical, active, ATR101, ATR-101, ATR101 Hydrochloride, ATR101 hydrochloride, ATR-101 Hydrochloride, ATR 101, ATR 101 Hydrochloride, Apoptosis, cancer, Diglyceride acyltransferase, Diacylglycerol acyltransferase
Field of Research
Cell Biology, Metabolism Research
Purity
99.25% (May vary between batches)
Solubility
DMSO:41.67 mg/mL (90.97 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.37 mM)
Smiles
Cl.CC (C) c1cccc (C (C) C) c1NC (=O) NCC1 (CCCC1) c1ccc (cc1) N (C) C
Molecular Formula
C27H40ClN3O
Molecular Weight
458.08
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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