Irdabisant
Product Specifications
CAS Number
1005402-19-6
Target
Histamine Receptor
Related Pathways
Immunology/Inflammation, Neuroscience, GPCR/G Protein
Purity
0.9996
Bioactivity
Irdabisant (CEP-26401) (CEP-26401) is a selective, orally active and blood-brain barrier (BBB) penetrant antagonist/inverse agonist of histamine H3 receptor (H3R) (rat H3R Ki= 7.2 nM, human H3R Ki= 2.0 nM) . Irdabisant exhibits relatively low inhibitory activity against hERG current (IC50= 13.8 μM) . Irdabisant exhibits cognition-enhancing and wake-promoting activities in the rat social recognition model. Irdabisant can be used for research on schizophrenia or cognitive impairment.
Smiles
O(CCCN1[C@H](C)CCC1)C2=CC=C(C=C2)C=3C=CC(=O)NN3
Molecular Formula
C18H23N3O2
Molecular Weight
313.39
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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