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(+) -KCC2 blocker 1

(+) -KCC2 blocker 1 is a potent and selective small-molecule inhibitor of the potassium-chloride cotransporter 2 (KCC2), exhibiting an IC50 of 0.4 μM. This compound is a valuable research tool for investigating the role of KCC2 in neuronal chloride homeostasis, synaptic inhibition, and related pathophysiology in both cellular and animal models of neurological disorders.

Product Specifications

CAS Number

1228439-71-1

Product Name Alternative

(+) KCC2 blocker 1, (+) -KCC-2 blocker 1, (+) KCC2 blocker 1, KCC2 blocker 1, KCC2, Potassium Channel, PotassiumChannel

Field of Research

Pharmacology & Drug Discovery

Purity

98.12% (May vary between batches)

Solubility

DMSO:50 mg/mL (120.34 mM)

Smiles

C (C1 (C (OCC2=CC=CC=C2) =O) N (C (C) =O) CCC1) C3=CC=C (S (C) (=O) =O) C=C3

Molecular Formula

C22H25NO5S

Molecular Weight

415.5

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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