Trilaciclib hydrochloride
Trilaciclib hydrochloride (G1T28 hydrochloride) is a potent and selective CDK4/6 inhibitor with IC50 values of 1 nM and 4 nM for CDK4 and CDK6, respectively. It is widely used in preclinical research to investigate cell cycle arrest, chemoprotection, and antitumor efficacy in both in vitro and in vivo cancer models.
Product Specifications
CAS Number
1977495-97-8
Product Name Alternative
Cyclin dependent kinase, CDK, CDK4/Cyc D1, Cdk4/cyclin D1, cdk6/cyclin D3, CDK6/CyclinD3, Inhibitor, inhibit, G1T28, G1T28 Hydrochloride, G1T28 hydrochloride, Trilaciclib, Trilaciclib hydrochloride, Trilaciclib Hydrochloride
Field of Research
Cell Biology, Pharmacology & Drug Discovery
Purity
98.61% (May vary between batches)
Solubility
DMSO:Insoluble; H2O:10 mM
Smiles
Cl.Cl.CN1CCN (CC1) c1ccc (Nc2ncc3cc4C (=O) NCC5 (CCCCC5) n4c3n2) nc1
Molecular Formula
C24H32Cl2N8O
Molecular Weight
519.47
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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