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Deruxtecan

Deruxtecan is a drug-linker conjugate featuring a DXd payload connected via a maleimide-GGFG peptide linker. It is a key component in the synthesis of ADCs like DS-8201 and U3-1402, enabling targeted cytotoxicity research in both in vitro and in vivo cancer models.

Product Specifications

CAS Number

1599440-13-7

Product Name Alternative

Inhibitor, inhibit, Camptothecins, DrugLinkerConjugatesforADC, DrugLinker Conjugates for ADC, Deruxtecan, Drug-Linker Conjugates for ADC

Field of Research

Pharmacology & Drug Discovery

Purity

97.03% (May vary between batches)

Solubility

10% DMSO+90% Corn Oil:2 mg/mL (1.93 mM) ; DMSO:262 mg/mL (253.37 mM)

Smiles

CC[C@@]1 (O) C (=O) OCc2c1cc1-c3nc4cc (F) c (C) c5CC[C@H] (NC (=O) COCNC (=O) CNC (=O) [C@H] (Cc6ccccc6) NC (=O) CNC (=O) CNC (=O) CCCCCN6C (=O) C=CC6=O) c (c3Cn1c2=O) c45

Molecular Formula

C52H56FN9O13

Molecular Weight

1034.05

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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