Dorzagliatin
Dorzagliatin (HMS5552) is a dual-acting glucokinase activator investigated for type 2 diabetes research. It enhances glycemic control and β-cell function, with studies demonstrating its efficacy in both in vitro enzymatic assays and in vivo animal models of diabetes.
Product Specifications
CAS Number
1191995-00-2
Product Name Alternative
Glycaemic, Glucokinase, Hexokinase D, Hexokinase IV, HMS-5552, HMS 5552, HMS5552, pancreatic, Inhibitor, inhibit, Dorzagliatin, diabetes, β-cell, type 2
Field of Research
Metabolism Research
Purity
98.52% (May vary between batches)
Solubility
DMSO:125 mg/mL (270.02 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (8.64 mM)
Smiles
CC (C) C[C@H] (N1CC (Oc2ccccc2Cl) =CC1=O) C (=O) Nc1ccn (C[C@@H] (O) CO) n1
Molecular Formula
C22H27ClN4O5
Molecular Weight
462.93
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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