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Dorzagliatin

Dorzagliatin (HMS5552) is a dual-acting glucokinase activator investigated for type 2 diabetes research. It enhances glycemic control and β-cell function, with studies demonstrating its efficacy in both in vitro enzymatic assays and in vivo animal models of diabetes.

Product Specifications

CAS Number

1191995-00-2

Product Name Alternative

Glycaemic, Glucokinase, Hexokinase D, Hexokinase IV, HMS-5552, HMS 5552, HMS5552, pancreatic, Inhibitor, inhibit, Dorzagliatin, diabetes, β-cell, type 2

Field of Research

Metabolism Research

Purity

98.52% (May vary between batches)

Solubility

DMSO:125 mg/mL (270.02 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (8.64 mM)

Smiles

CC (C) C[C@H] (N1CC (Oc2ccccc2Cl) =CC1=O) C (=O) Nc1ccn (C[C@@H] (O) CO) n1

Molecular Formula

C22H27ClN4O5

Molecular Weight

462.93

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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