JNJ-1661010
JNJ-1661010 (Takeda-25) is a potent and selective inhibitor of fatty acid amide hydrolase-1 (FAAH-1), exhibiting IC50 values of 10 nM (rat) and 12 nM (human) with over 100-fold selectivity versus FAAH-2. This compound is a valuable pharmacological tool for investigating the endocannabinoid system in both in vitro and in vivo research models.
Product Specifications
CAS Number
681136-29-8
Product Name Alternative
N-Phenyl-4- (3-phenyl-1,2,4-thiadiazol-5-yl) -1-piperazinecarboxamide
Field of Research
Neuroscience
Purity
>98%
Bioactivity
FAAH inhibitor
Form
Powder
Solubility
Soluble in DMSO (up to 25 mg/ml) .
Smiles
O=C (Nc1ccccc1) N1CCN (CC1) c1nc (ns1) -c1ccccc1
Molecular Formula
C19H19N5OS
Molecular Weight
365.46
Storage Conditions
-20°C
Notes
For research use only.
Other Product Names
4- (3-Phenyl-[1,2,4]thizdiazol-5-yl) -piperazine-1-carboxylic acid phenylamide
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