Nitroaspirin
Nitroaspirin (NCX 4016) is a nitric oxide-donating aspirin derivative that acts as an irreversible COX-1 inhibitor with antiplatelet effects. It demonstrates research utility in oncology, inducing apoptosis and cell cycle arrest in resistant ovarian cancer cells in vitro by suppressing EGFR/PI3K/STAT3 pathways and modulating Bcl-2 proteins.
Product Specifications
CAS Number
175033-36-0
Product Name Alternative
Inhibitor, NCX4016, NCX-4016, NCX 4016, Nitroaspirin, inhibit, COX, COX-1, Cyclooxygenase, Apoptosis
Field of Research
Cell Biology, Immunology & Inflammation, Neuroscience
Purity
98.45% (May vary between batches)
Solubility
DMSO:55 mg/mL (166.02 mM) ;10% DMSO+90% Corn Oil:5 mg/mL (15.09 mM)
Smiles
O (C (C) =O) C1=C (C (OC2=CC (CON (=O) =O) =CC=C2) =O) C=CC=C1
Molecular Formula
C16H13NO7
Molecular Weight
331.28
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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