PNU-159682
PNU-159682 is a potent DNA topoisomerase II inhibitor derived from the anthracycline nemorubicin. This cytotoxic metabolite is utilized in cancer research to study its antitumor mechanisms in both in vitro and in vivo experimental models.
Product Specifications
CAS Number
202350-68-3
Product Name Alternative
NMS249, NHL, non-Hodgkin's lymphoma, inhibit, Inhibitor, EDV nanocell, acute myeloid leukemia, ADC Payload, ADCs Toxin, ADCCytotoxin, ADC Cytotoxin, AML, Daunorubicins/Doxorubicins, Topoisomerase, topoisomerase I, PNU159682, PNU-159682, PNU 159682
Field of Research
Molecular Biology
Purity
98.24% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (5.14 mM) ; DMSO:96.7 mg/mL (150.71 mM)
Smiles
CO[C@H]1OCCN2[C@H]3C[C@H] (O[C@H]4C[C@@] (O) (Cc5c (O) c6C (=O) c7cccc (OC) c7C (=O) c6c (O) c45) C (=O) CO) O[C@@H] (C) [C@H]3O[C@H]12
Molecular Formula
C32H35NO13
Molecular Weight
641.62
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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