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RPI-1

RPI-1 is a potent and selective ATP-competitive inhibitor of the Ret tyrosine kinase. It is utilized in biochemical and cellular assays to investigate Ret-driven signaling pathways and has been employed in preclinical research models to study cancers like medullary thyroid carcinoma.

Product Specifications

CAS Number

269730-03-2

Product Name Alternative

Inhibitor, HGFR, medullary, inhibit, kinase, oral, PLCγ, Met, carcinoma, cells, cMet/HGFR, c-Met, cMet, cRET, CTND1, phosphorylation, thyroid, proliferation, RET, RPI 1, RPI1, RPI-1, tyrosine

Field of Research

Cell Biology, Metabolism Research, Neuroscience, Signal Transduction

Purity

≥95% (May vary between batches)

Solubility

DMSO:5.5 mg/mL (18.5 mM)

Smiles

COc1cc2NC (=O) \C (=C/c3ccc (O) cc3) c2cc1OC

Molecular Formula

C17H15NO4

Molecular Weight

297.31

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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