SCH900776
SCH900776 (MK-8776) is a selective Chk1 kinase inhibitor investigated as a chemosensitizer and radiosensitizer in cancer research. It has been utilized in both in vitro and in vivo studies to abrogate cell cycle checkpoints and enhance the efficacy of DNA-damaging agents like gemcitabine and radiation.
Product Specifications
CAS Number
891494-63-6
Product Name Alternative
CDK2, Checkpoint Kinase (Chk), Chk1, Chk2, MK 8776, MK8776, MK-8776, inhibit, Inhibitor, SCH 900776, SCH900776, SCH-900776
Field of Research
Cell Biology
Purity
96.69% (May vary between batches)
Solubility
DMSO:100 mg/mL (265.78 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (10.63 mM)
Smiles
Cn1cc (cn1) -c1cnn2c (N) c (Br) c (nc12) [C@@H]1CCCNC1
Molecular Formula
C15H18BrN7
Molecular Weight
376.25
Storage Conditions
-20°C
Notes
For research use only.
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