CCT 137690
CCT 137690 is a potent and orally bioavailable small molecule inhibitor targeting Aurora kinases A, B, and C with IC50 values of 15, 25, and 19 nM, respectively. It is a valuable research tool for studying mitotic regulation and has demonstrated anti-proliferative activity in various cancer cell lines in vitro.
Product Specifications
CAS Number
1095382-05-0
Product Name Alternative
Aurora B, Aurora Kinase, Aurora C, AuroraKinase, Aurora A, Apoptosis, CCT137690, CCT-137690, CCT 137690, inhibit, Inhibitor
Field of Research
Cell Biology, Epigenetics & Chromatin
Purity
98.51% (May vary between batches)
Solubility
DMSO:55.2 mg/mL (100.09 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (1.81 mM)
Smiles
CN1CCN (CC1) c1ccc (cc1) -c1nc2c (N3CCN (Cc4cc (C) on4) CC3) c (Br) cnc2[nH]1
Molecular Formula
C26H31BrN8O
Molecular Weight
551.48
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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