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PPIB Antibody - C-terminal region : HRP (ARP44366_T100-HRP)

Selected Variant

ARP44366_T100-HRP

Size: 100 µL

Product Specifications

Gene Name

Peptidylprolyl isomerase B (cyclophilin B)

Gene Aliases

B, OI9, CYPB, SCYLP, CYP-S1, HEL-S-39

Gene ID

5479

Swiss Prot

A8K534

Accession Number

NP_000933

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human PPIB

Target

PPIB is a cyclosporine-binding protein and is mainly located within the endoplasmic reticulum. It is associated with the secretory pathway and released in biological fluids. This protein can bind to cells derived from T- and B-lymphocytes, and may regulate cyclosporine A-mediated immunosuppression. Western blots using two different antibodies against two unique regions of this protein target confirm the same apparent molecular weight in our tests.The protein encoded by this gene is a cyclosporine-binding protein and is mainly located within the endoplasmic reticulum. It is associated with the secretory pathway and released in biological fluids. This protein can bind to cells derived from T- and B-lymphocytes, and may regulate cyclosporine A-mediated immunosuppression.

Partner Proteins

BANP; UBQLN1; SGTA; PEX19; UBC; MDM2; DDIT3; WWOX; SUZ12; EED; BMI1; rev; RRM1; PPP5C; PFKP; GAPDH; HECW2; FBXO6; UBD; CFTR; ATP12A; VKORC1; OS9; MAGT1; SUGP1; LSM4; TIMM44; SCO2; ZC3H11A; UBL4A; RBMS1; RANGAP1; PCBP2; P4HB; HSPA5; PDIA3; DHX9; ACAA1; MRP

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

IHC, WB

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 86%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

24kDa

References & Citations

Watashi, K., (2005) Mol. Cell 19 (1), 111-122

Shipping Conditions

Wet Ice

Protein Length

216

NCBI Gene Symbol

PPIB

NCBI GB Accession Number

PPIB

Host or Source

Rabbit

Protein Name

Peptidyl-prolyl cis-trans isomerase B

Nucleotide Accession Number

NM_000942

Peptide Sequence

VVFGKVLEGMEVVRKVESTKTDSRDKPLKDVIIADCGKIEVEKPFAIAKE

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