A-1210477
A-1210477 is a potent and selective small molecule dual inhibitor of MCL-1 and Bcl-2, with a Ki of 0.454 nM and an IC50 of 26.2 nM. It is widely used in cancer research, particularly in studies of apoptosis, for both in vitro cellular assays and in vivo xenograft models to investigate hematological malignancies.
Product Specifications
CAS Number
1668553-26-1
Product Name Alternative
Apoptosis, Bcl-2 Family, A 1210477, A1210477, A-1210477, inhibit, Inhibitor, Mcl-1
Field of Research
Cell Biology
Purity
98.89% (May vary between batches)
Solubility
DMSO:Insoluble; H2O:10 mM
Smiles
C (CN1CCOCC1) N2C3=C (C=CC=C3C (CCCOC=4C5=C (C=CC4) C=CC=C5) =C2C (O) =O) C6=C (COC7=CC=C (C=C7) N8CCN (S (N (C) C) (=O) =O) CC8) N (C) N=C6C
Molecular Formula
C46H55N7O7S
Molecular Weight
850.04
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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