DGY-06-116
DGY-06-116 is a potent, selective, and irreversible covalent inhibitor, demonstrating high potency against Src (IC50 = 3 nM) and weaker activity against FGFR1 (IC50 = 8340 nM) . This small molecule is a valuable chemical probe for cancer research, facilitating the study of Src-dependent signaling pathways in both cellular and biochemical assays.
Product Specifications
CAS Number
2556836-50-9
Product Name Alternative
DGY 06 116, DGY06116, DGY-06-116, FGFR1, Src
Field of Research
Cardiovascular Research, Signal Transduction
Purity
97.65% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (6.7 mM) ; DMSO:100 mg/mL (167.47 mM)
Smiles
CN1CCN (CC1) c1ccc (Nc2ncc (C (=O) Nc3c (C) cccc3Cl) c (Nc3ccccc3NC (=O) C=C) n2) cc1
Molecular Formula
C32H33ClN8O2
Molecular Weight
597.11
Storage Conditions
-20°C
Notes
For research use only.
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