MDR-652
MDR-652 is a potent, nonpungent TRPV1 agonist with high affinity (Ki: 11.4 nM hTRPV1) and functional potency (EC50: 5.05 nM hTRPV1) . Its strong topical analgesic properties support research in pain pathways, inflammation, and neurobiology, applicable in both in vitro receptor studies and in vivo models of nociception.
Product Specifications
CAS Number
1933528-96-1
Product Name Alternative
Activity, analgesic, MDR 652, MDR652, MDR-652, hTRPV1, ligand, Inhibitor, inhibit, pain, neuropathic, Transient receptor potential channels, TRP Channel, TRPChannel, TRPV Channel, TRPV1, TRPVChannel
Field of Research
Pharmacology & Drug Discovery
Purity
95.04% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (11.16 mM) ; DMSO:249 mg/mL (555.87 mM)
Smiles
CC (C) (C) c1nc (c (CNC (=O) Nc2ccc (CO) c (F) c2) s1) -c1cccc (Cl) c1
Molecular Formula
C22H23ClFN3O2S
Molecular Weight
447.95
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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