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RBN012759

RBN012759 is a potent and highly selective inhibitor of PARP14, exhibiting an IC50 of 3 nM and >300-fold selectivity over other PARP family members. This small molecule is a valuable chemical probe for studying PARP14's role in cancer, inflammation, and metabolism in both cellular and animal models.

Product Specifications

CAS Number

2360851-29-0

Product Name Alternative

Cancer, Inhibitor, inflammatory, inhibit, macrophage, PARP, PARP14, poly ADP ribose polymerase, RBN 012759, RBN012759, RBN-012759, pro-tumor

Field of Research

Epigenetics & Chromatin, Molecular Biology

Purity

98.87% (May vary between batches)

Solubility

DMSO:12 mg/mL (31.71 mM)

Smiles

O[C@H]1CC[C@@H] (CC1) SCc1nc2cc (OCC3CC3) cc (F) c2c (=O) [nH]1

Molecular Formula

C19H23FN2O3S

Molecular Weight

378.46

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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