DARS1 (NM_001349) Human Recombinant Protein
Product Specifications
Background
This gene encodes a member of a multienzyme complex that functions in mediating the attachment of amino acids to their cognate tRNAs. The encoded protein ligates L-aspartate to tRNA (Asp) . Mutations in this gene have been found in patients showing hypomyelination with brainstem and spinal cord involvement and leg spasticity. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2014]
Synonyms
AspRS; DARS; HBSL
Gene ID
1615
UniProt
P14868, A0A140VJW5
Accession Number mRNA
NM_001349
Chromosomal Location
2q21.3
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Aminoacyl-tRNA biosynthesis
Field of Research
Aminoacyl-tRNA biosynthesis
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Molecular Weight
57 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
DARS1
Species
Human
Protein ID
NP_001340
Overview
Recombinant protein of human aspartyl-tRNA synthetase (DARS)
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/1615
Uniprot URL
https://www.uniprot.org/uniprot/P14868
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_001349
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_001340
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