2,5-dimethyl Celecoxib
2,5-dimethyl Celecoxib is a celecoxib-based small molecule that selectively inhibits microsomal prostaglandin E synthase-1 (mPGES-1), a pivotal enzyme in inflammatory prostaglandin E2 biosynthesis. This inhibitor is utilized in research to investigate inflammation, pain, and cancer pathways in both cellular and animal models.
Product Specifications
CAS Number
457639-26-8
Product Name Alternative
Field of Research
Cell Biology, Immunology & Inflammation, Pharmacology & Drug Discovery, Signal Transduction, Stem Cell & Developmental Biology
Purity
99.85% (May vary between batches)
Solubility
Ethanol:3 mg/mL (7.59 mM) ; DMSO:60 mg/mL (151.75 mM) ; DMF:5 mg/mL (12.65 mM) ; DMSO:PBS (pH 7.2) (1:3) :0.25 mg/mL (0.63 mM)
Smiles
CC1=CC (C2=CC (=NN2C2=CC=C (C=C2) S (N) (=O) =O) C (F) (F) F) =C (C) C=C1
Molecular Formula
C18H16F3N3O2S
Molecular Weight
395.4
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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