AZD1981
AZD1981 is a potent and selective CRTh2 (DP2) receptor antagonist with an IC50 of 4 nM, demonstrating over 1000-fold selectivity against DP1 and numerous other targets. It has been utilized in both in vitro mechanistic studies and in vivo clinical trials investigating asthma and other inflammatory conditions.
Product Specifications
CAS Number
802904-66-1
Product Name Alternative
ProstaglandinReceptor, Prostaglandin Receptor, AZD 1981, AZD1981, AZD-1981, CRTh2 (DP2) receptor, Inhibitor, inhibit
Field of Research
Immunology & Inflammation, Metabolism Research, Pharmacology & Drug Discovery
Purity
98.59% (May vary between batches)
Solubility
H2O:< 1 mg/mL (insoluble or slightly soluble) ; Ethanol:< 1 mg/mL (insoluble or slightly soluble) ;10% DMSO+90% Corn Oil:0.5 mg/mL (1.29 mM) ; DMSO:9 mg/mL (23.14 mM)
Smiles
CC (=O) Nc1cccc2n (CC (O) =O) c (C) c (Sc3ccc (Cl) cc3) c12
Molecular Formula
C19H17ClN2O3S
Molecular Weight
388.87
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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