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[11C]MP 10

[11C]MP 10 (PF-2545920) is a highly potent and selective inhibitor of PDE10A, exhibiting an IC50 of 0.37 nM and >1000-fold selectivity over other PDEs. This radiolabeled tracer is used in preclinical and clinical PET imaging studies to investigate PDE10A expression and occupancy in the brain for neurological and psychiatric research.

Product Specifications

CAS Number

1292799-56-4

Product Name Alternative

[11C]MP 10, PDE10A, Mardepodect, PF2545920, PF-2545920, PF 2545920

Field of Research

Metabolism Research

Purity

99.50% (May vary between batches)

Solubility

Ethanol:69 mg/mL (176.27 mM) ; DMSO:79 mg/mL (201.81 mM)

Smiles

[11CH3]N1N=C (C (=C1) C=2C=CN=CC2) C3=CC=C (OCC4=NC5=C (C=C4) C=CC=C5) C=C3

Molecular Formula

C25H20N4O

Molecular Weight

391.45

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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