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(E/Z) -Rigosertib sodium

ON-01910 (Rigosertib) is a potent and selective non-ATP-competitive inhibitor of PLK1, demonstrating pro-apoptotic activity in cancer cells through PI3K/Akt pathway inhibition and oxidative stress induction. It is widely used in oncology research, with studies in both cellular and animal models exploring its mechanisms and therapeutic potential against various malignancies.

Product Specifications

CAS Number

1225497-78-8

Product Name Alternative

(E/Z) ON-01910 sodium, ON-01910, ON 01910, ON01910, PLK1

Field of Research

Cell Biology

Purity

97.16% (May vary between batches)

Solubility

DMSO:94 mg/mL (198.53 mM)

Smiles

[Na+].COc1cc (OC) c (C=CS (=O) (=O) Cc2ccc (OC) c (NCC ([O-]) =O) c2) c (OC) c1

Molecular Formula

C21H24NNaO8S

Molecular Weight

473.47

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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