AZD 6482
AZD 6482 (KIN-193) is a highly potent and selective p110β/PI3Kβ inhibitor, demonstrating IC50 values of 0.69 nM and 10 nM, respectively. It effectively suppresses AKT signaling and inhibits tumor growth in models driven by p110β activation or PTEN deficiency, making it a valuable tool for oncology research in both cellular and animal studies.
Product Specifications
CAS Number
1173900-33-8
Product Name Alternative
Phosphoinositide 3-kinase, PI3Kβ, PI3Kγ, PI3Kδ, PI3K, PI3Kα, KIN193, KIN-193, KIN 193, Inhibitor, inhibit, AZD 6482, AZD6482, AZD-6482, Autophagy, DNA-PK, DNAPK
Field of Research
Cell Biology, Molecular Biology, Signal Transduction
Purity
99.79% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.9 mM) ; DMSO:45 mg/mL (110.17 mM)
Smiles
C[C@@H] (Nc1ccccc1C (O) =O) c1cc (C) cn2c1nc (cc2=O) N1CCOCC1
Molecular Formula
C22H24N4O4
Molecular Weight
408.45
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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