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CVN293

Product Specifications

CAS Number

2815296-08-1

Target

NOD-like Receptor (NLR), NOD, Potassium Channel, IL Receptor

Related Pathways

Immunology/Inflammation, NF-κB, Membrane transporter/Ion channel

Purity

0.995

Bioactivity

CVN293 is a selective inhibitor of the potassium channel KCNK13, with the advantages of brain permeability and oral bioavailability. It inhibits the production of the pro-inflammatory cytokine IL-1β induced by NLRP3 in microglia and can be used for research into neurodegenerative diseases.

Smiles

C(N1C(=NC=2C1=C(F)C=CC2)C=3C(N)=NON3)C4=CC=CN=N4

Molecular Formula

C14H10FN7O

Molecular Weight

311.27

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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