A-674563 2HCl (552325-73-2 (fb-2hcl) )
A-674563 2HCl is a potent and selective Akt1 inhibitor with a Ki of 11 nM. It exhibits modest activity against PKA and over 30-fold selectivity versus PKC. This tool compound is used in vitro and in vivo to study the PI3K/Akt signaling pathway in cancer and metabolic research.
Product Specifications
Product Name Alternative
CDK2, A-674563 2HCl (552325-73-2 (fb-2hcl) ), A674563 2HCl (552325732 (fb2hcl) ), A 674563 2HCl (552325 73 2 (fb 2hcl) ), Akt1, ERK2, PKA, PKCδ
Field of Research
Cell Biology, Epigenetics & Chromatin, Signal Transduction
Purity
94.66% (May vary between batches)
Solubility
DMSO:27.5 mg/mL (63.75 mM)
Smiles
Cl.Cl.Cc1n[nH]c2ccc (cc12) -c1cncc (OC[C@@H] (N) Cc2ccccc2) c1
Molecular Formula
C22H24Cl2N4O
Molecular Weight
431.36
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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