PF-04859989 HCl
PF-04859989 HCl is a brain-penetrant, irreversible inhibitor of kynurenine aminotransferase II (KAT II), the primary enzyme for cerebral kynurenic acid synthesis. This tool compound is used in neuroscience research to study the KAT II pathway in models of psychiatric and neurological disorders, both in vitro and in vivo.
Product Specifications
CAS Number
177943-33-8
Product Name Alternative
Kynurenine aminotransferase (KAT) II, midbrain, neurons, cognitive , impairment, PF 04859989, PF 04859989 HCl, PF-04859989 HCl, PF-04859989HCl, PF04859989, PF04859989 HCl, PF-04859989
Purity
98.28% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (18.63 mM) ; DMSO:100 mg/mL (465.87 mM) ; H2O:100 mg/mL (465.87 mM)
Smiles
Cl.N[C@H]1Cc2ccccc2N (O) C1=O
Molecular Formula
C9H11ClN2O2
Molecular Weight
214.65
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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