Phlorizin
Phlorizin is a natural, non-selective SGLT inhibitor isolated from apple, exhibiting inhibitory activity against hSGLT1 (Ki=300 nM) and hSGLT2 (Ki=39 nM) . It is widely used in research to study glucose transport mechanisms in renal physiology and diabetes, both in vitro and in animal models.
Product Specifications
CAS Number
60-81-1
Product Name Alternative
Inhibit, NSC 2833, Na+/K+ ATPase, NSC2833, NSC-2833, Floridzin, Inhibitor, hSGLT1, hSGLT2, Sodium potassium pump, Sodium-dependent glucose cotransporters, Phlorizin, Phloridzin, SGLT
Field of Research
Pharmacology & Drug Discovery
Purity
98.00% (May vary between batches)
Solubility
DMSO:118 mg/mL (270.39 mM) ; Ethanol:43.6 mg/mL (99.91 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (9.17 mM) ; H2O:< 1 mg/mL (insoluble or slightly soluble)
Smiles
C (CCC1=CC=C (O) C=C1) (=O) C2=C (O[C@@H]3O[C@H] (CO) [C@@H] (O) [C@H] (O) [C@H]3O) C=C (O) C=C2O
Molecular Formula
C21H24O10
Molecular Weight
436.41
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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