Carotegrast methyl
Carotegrast methyl (AJM300) is an orally bioavailable small molecule antagonist that selectively targets both α4β1 and α4β7 integrins. It is a research tool for investigating integrin function in inflammatory and autoimmune diseases, with demonstrated utility in both in vitro adhesion assays and in vivo models of colitis.
Product Specifications
CAS Number
401905-67-7
Product Name Alternative
AJM 300, AJM300, AJM-300, Carotegrast methyl, colitis, Inhibitor, Integrin, HCA2969, inhibit, Jurkat, orally, TK-1, RPMI-8866, α4β1 integrin
Field of Research
Signal Transduction
Purity
98.73% (May vary between batches)
Solubility
DMSO:100 mg/mL (175.61 mM)
Smiles
COC (=O) [C@H] (Cc1ccc (cc1) -n1c (=O) n (C) c2ccc (cc2c1=O) N (C) C) NC (=O) c1c (Cl) cccc1Cl
Molecular Formula
C28H26Cl2N4O5
Molecular Weight
569.44
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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