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Indole-3-carbinol

Indole-3-carbinol (I3C) is a natural, orally bioavailable compound derived from glucobrassicanin. It functions as an inhibitor of NF-κB signaling by blocking IκBα kinase activation. This small molecule is widely used in research areas such as cancer, inflammation, and immunology for both in vitro and in vivo experimental studies.

Product Specifications

CAS Number

700-06-1

Product Name Alternative

Inhibitor, I3C, EndogenousMetabolite, Indole 3 carbinol, Indole3carbinol, Indole-3-carbinol, Indole-3-Methanol, inhibit, p53, Nuclear factor-kappaB, Nuclear factor-κB, NF-κB, NFκB, NFkB, NF-kB, 3-Indolemethanol, AhR, ArylHydrocarbonReceptor, Aryl Hydrocarbon Receptor, E1 activating enzyme, E1 Enzyme, E2 Enzyme, E2 conjugating enzyme, E1Enzyme, E1/E2/E3 Enzyme, Endogenous Metabolite, E3 ligating enzyme, E3Enzyme, E3 Enzyme, E2Enzyme, Ubiquitin conjugating enzyme, Ubiquitin ligase, Ubiquitin activating enzyme

Field of Research

Cell Biology, Immunology & Inflammation, Metabolism Research, Protein Biochemistry, Signal Transduction

Purity

97.06% (May vary between batches)

Solubility

DMSO:1.61 mg/mL (10.94 mM) ; Ethanol:28 mg/mL (190.26 mM) ; H2O:7 mg/mL (47.56 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (6.79 mM)

Smiles

C (O) C=1C=2C (NC1) =CC=CC2

Molecular Formula

C9H9NO

Molecular Weight

147.17

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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