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ISO-1

ISO-1 is a small molecule MIF antagonist that inhibits dopachrome tautomerase activity. It suppresses NF-κB activation and TNF-α secretion in LPS-stimulated macrophages, making it a valuable tool for studying inflammation, sepsis, and autoimmune diseases in both cellular and animal models.

Product Specifications

CAS Number

478336-92-4

Product Name Alternative

Dopachrome tautomerase, MIF Antagonist, inhibit, ISO 1, ISO1, ISO-1, Inhibitor

Field of Research

Cell Biology, Neuroscience

Purity

>98%

Bioactivity

Macrophage migration inhibitory factor (MIF) antagonist

Form

Powder

Solubility

Soluble in DMSO (up to 25 mg/ml) .

Smiles

COC (=O) CC1CC (=NO1) c1ccc (O) cc1

Molecular Formula

C12H13NO4

Molecular Weight

235.24

Storage Conditions

-20°C

Notes

For research use only.

Other Product Names

(S, R) -3- (4-Hydroxyphenyl) -4,5-dihydro-5-isoxazole acetic acid, methyl ester

Available Sizes

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