Rolapitant
Rolapitant hydrochloride is a selective neurokinin-1 (NK1) receptor antagonist used in research to study antiemetic mechanisms. It is applied in preclinical models of chemotherapy-induced nausea and vomiting (CINV), with studies demonstrating its efficacy in both in vitro binding assays and in vivo animal models.
Product Specifications
CAS Number
552292-08-7
Product Name Alternative
Long-acting, inhibit, orally active, NK receptor, NK1, Neurokinin receptor, Neurokinin Receptor, Neurokininreceptor, Mongolian Gerbils, Inhibitor, emesis, ferret, foot tapping, anti-emetic, retches, Rolapitant, SCH 619734, SCH619734, SCH-619734, Tachykinin receptor, vomits
Field of Research
Neuroscience, Pharmacology & Drug Discovery
Purity
98.34% (May vary between batches)
Solubility
DMSO:55 mg/mL (109.89 mM)
Smiles
[H][C@] (C) (OC[C@]1 (CC[C@]2 (CCC (=O) N2) CN1) c1ccccc1) c1cc (cc (c1) C (F) (F) F) C (F) (F) F
Molecular Formula
C25H26F6N2O2
Molecular Weight
500.48
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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