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DDO-02267

DDO-02267 is a potent, selective covalent inhibitor of the RNA demethylase ALKBH5 (IC50 = 0.49 μM) . It elevates m6A levels and disrupts the ALKBH5-AXL signaling axis, serving as a valuable chemical probe for studying m6A biology in both cellular and in vivo research contexts.

Product Specifications

CAS Number

2919768-58-2

Field of Research

Cardiovascular Research, Metabolism Research, Signal Transduction

Smiles

O=CC=1C=C (C=2C=CC=CC2C1O) S (=O) (=O) NC (=O) C3=NC=CC (=C3) C (=O) O

Molecular Formula

C18H12N2O7S

Molecular Weight

400.362

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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