4-CPPC
4-CPPC is a selective small molecule inhibitor of macrophage migration inhibitory factor-2 (MIF-2) with an IC50 of 27 μM, showing over 16-fold selectivity versus MIF-1. It blocks MIF-2 binding to its receptor CD74 and inhibits downstream ERK1/2 phosphorylation in human fibroblasts, making it a useful tool for studying MIF-2-specific signaling pathways in immunological and inflammatory research.
Product Specifications
CAS Number
29553-70-6
Product Name Alternative
4CPPC, 4-CPPC, 4 CPPC
Field of Research
Immunology & Inflammation
Purity
97.10% (May vary between batches)
Solubility
DMSO:2.88 mg/mL (10.03 mM)
Smiles
OC (=O) C1=CC=CC (=C1) C1=CC (=NC=C1C (O) =O) C (O) =O
Molecular Formula
C14H9NO6
Molecular Weight
287.22
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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