Forsythoside B
Forsythoside B is a bioactive small molecule that binds lipopolysaccharide (LPS), suppressing NF-κB activation and the subsequent inflammatory cascade. It demonstrates potent neuro- and cardioprotective effects in ischemia-reperfusion injury models, attenuates blood-brain barrier disruption, and exhibits significant antisepsis activity by reducing systemic inflammatory mediators.
Product Specifications
CAS Number
81525-13-5
Product Name Alternative
Nuclear factor-kappaB, Nuclear factor-κB, NF-κB, NFkB, NFκB, NF-kB, inhibit, Inhibitor, Forsythoside B, TNFR, TNF Receptor, Tumor Necrosis Factor Receptor
Field of Research
Cell Biology, Signal Transduction
Purity
96.52% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2.00 mg/mL (2.64 mM) ; DMSO:55.00 mg/mL (72.68 mM)
Smiles
C[C@@H]1O[C@@H] (O[C@@H]2[C@@H] (O) [C@H] (OCCc3ccc (O) c (O) c3) O[C@H] (CO[C@@H]3OC[C@] (O) (CO) [C@H]3O) [C@H]2OC (=O) \C=C\c2ccc (O) c (O) c2) [C@H] (O) [C@H] (O) [C@H]1O
Molecular Formula
C34H44O19
Molecular Weight
756.70
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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