TH5427
TH5427 is a potent and selective small molecule inhibitor of NUDT5, exhibiting an IC50 of 29 nM in MG assays. This compound is a valuable chemical probe for studying NUDT5's role in ADP-ribose metabolism and related signaling pathways in cellular and biochemical research contexts.
Product Specifications
CAS Number
2253744-56-6
Product Name Alternative
Breast cancer, ADP-ribose, ATP synthesis, NUDIX hydrolase, NUDIXhydrolase, NUDT5, inhibit, Inhibitor, TH5427, TH-5427, TH 5427, progestin-dependent, proliferation
Field of Research
Cell Biology, Metabolism Research, Molecular Biology
Purity
99.54% (May vary between batches)
Solubility
H2O:< 1 mg/mL (insoluble or slightly soluble) ; DMSO:3.67 mg/mL (7.47 mM)
Smiles
C (N1C2=C (N=C1N3CCNCC3) N (C) C (=O) N (C) C2=O) C=4OC (=NN4) C5=CC (Cl) =C (Cl) C=C5
Molecular Formula
C20H20Cl2N8O3
Molecular Weight
491.33
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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