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Fezolinetant

Fezolinetant (ESN-364) is a selective neurokinin-3 (NK3) receptor antagonist under investigation for the treatment of vasomotor symptoms associated with menopause. Its mechanism of action has been validated in both in vitro binding assays and in vivo preclinical models of thermoregulation.

Product Specifications

CAS Number

1629229-37-3

Product Name Alternative

Neurokinin Receptor, Neurokinin receptor, Neurokininreceptor, NK3, NK receptor, inhibit, Inhibitor, ESN 364, ESN364, ESN-364, Fezolinetant, Tachykinin receptor

Field of Research

Neuroscience, Pharmacology & Drug Discovery

Purity

98.62% (May vary between batches)

Solubility

DMSO:10 mg/mL (27.9 mM)

Smiles

C[C@H]1N (CCn2c1nnc2-c1nc (C) ns1) C (=O) c1ccc (F) cc1

Molecular Formula

C16H15FN6OS

Molecular Weight

358.39

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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