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CD2 Mouse Monoclonal Antibody [Clone ID: UMLBI86]

Product Specifications

Background

CD2 is a surface antigen of the human T-lymphocyte lineage that is expressed on all peripheral blood T cells (summarized by Sewell et al., 1986 [PubMed 3490670]) . It is one of the earliest T-cell markers, being present on more than 95% of thymocytes; it is also found on some natural killer cells but not on B lymphocytes. Monoclonal antibodies directed against CD2 inhibit the formation of rosettes with sheep erythrocytes, indicating that CD2 is the erythrocyte receptor or is closely associated with it. [supplied by OMIM, Jul 2010]

Synonyms

LFA-2; SRBC; T11

Gene Name

Homo sapiens CD2 molecule (CD2), transcript variant 2, mRNA.

Gene ID

914

UniProt

P06729

Conjugation

Unconjugated

Related Pathways

Cell adhesion molecules (CAMs), Hematopoietic cell lineage

Field of Research

Cell adhesion molecules (CAMs), Hematopoietic cell lineage

Dilution

IHC 1:100

Form

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Buffer

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Function

Druggable Genome, Transmembrane

Storage Conditions

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Symbol

CD2

Overview

Carrier-free (BSA/glycerol-free) CD2 mouse monoclonal antibody, clone UMLBI86

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/?term=914

Uniprot URL

https://www.uniprot.org/uniprot/P06729

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