Fmoc-Val-Cit-PAB
Fmoc-Val-Cit-PAB is a protease-cleavable linker used in the construction of antibody-drug conjugates (ADCs) for targeted cancer therapy. It enables the controlled release of cytotoxic payloads in both in vitro and in vivo research models, facilitating the study of ADC efficacy and stability.
Product Specifications
CAS Number
159858-22-7
Product Name Alternative
Inhibit, Inhibitor, Fmoc Val Cit PAB, FmocValCitPAB, Fmoc-Val-Cit-PAB, Antibody-drug conjugates linkers, ADC Linker, ADCLinker, ADC Linkers
Field of Research
Signal Transduction
Purity
97.18% (May vary between batches)
Solubility
DMSO:123.75 mg/mL (205.67 mM)
Smiles
CC (C) [C@H] (NC (=O) OCC1c2ccccc2-c2ccccc12) C (=O) N[C@@H] (CCCNC (N) =O) C (=O) Nc1ccc (CO) cc1
Molecular Formula
C33H39N5O6
Molecular Weight
601.69
Storage Conditions
-20°C
Notes
For research use only.
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