GSK2193874
GSK2193874 is a potent and selective orally bioavailable TRPV4 channel antagonist. It is utilized in research to investigate TRPV4's role in pulmonary edema, neuropathic pain, and skeletal disorders, employing both in vitro cellular assays and in vivo animal models.
Product Specifications
CAS Number
1336960-13-4
Product Name Alternative
Inhibit, Inhibitor, GSK 2193874, GSK2193874, GSK-2193874, TRP Channel, TRPChannel, TRPV Channel, TRPV4, TRPVChannel, Transient receptor potential channels
Field of Research
Pharmacology & Drug Discovery
Purity
≥95% (May vary between batches)
Solubility
DMSO:81.67 mg/mL (118.09 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (5.78 mM)
Smiles
FC (F) (F) c1cccc (c1) -c1nc2cc (Br) ccc2c (C (=O) NC2 (CC2) c2ccccc2) c1CN1CCC (CC1) N1CCCCC1
Molecular Formula
C37H38BrF3N4O
Molecular Weight
691.62
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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