Reparixin
Reparixin is a potent small molecule dual CXCR1/CXCR2 antagonist, exhibiting strong inhibition of CXCR1-mediated chemotaxis (IC50=1 nM) and weaker activity against CXCR2 (IC50=100 nM) . It is widely used in research to investigate the role of IL-8 signaling in inflammation, cancer metastasis, and ischemia-reperfusion injury in both cellular and animal models.
Product Specifications
CAS Number
266359-83-5
Product Name Alternative
DF 1681Y; Repertaxin
Field of Research
Cancer Biology
Purity
>98%
Bioactivity
CXCR1/2 allosteric antagonist
Form
Powder
Solubility
Soluble in DMSO (up to 100 mg/ml) or in Ethanol up to 25 mg/ml)
Smiles
CC (C) Cc1ccc (cc1) [C@@H] (C) C (=O) NS (C) (=O) =O
Molecular Formula
C14H21NO3S
Molecular Weight
283.39
Storage Conditions
-20°C
Notes
For research use only.
Other Product Names
αR-Methyl-4- (2-methylpropyl) -N- (methylsulfonyl) -benzeneacetamide
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