SIT (SIT1) (NM_014450) Human Recombinant Protein
Product Specifications
Background
Negatively regulates TCR (T-cell antigen receptor) -mediated signaling in T-cells. Involved in positive selection of T-cells.[UniProtKB/Swiss-Prot Function]
Overview
Recombinant protein of human signaling threshold regulating transmembrane adaptor 1 (SIT1)
Synonyms
SIT; SIT-R
Gene ID
27240
UniProt
Q9Y3P8
Accession Number mRNA
NM_014450
Chromosomal Location
9p13.3
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Transmembrane
Molecular Weight
20.9 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
SIT1
Species
Human
Protein ID
NP_055265
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/27240
Uniprot URL
https://www.uniprot.org/uniprot/Q9Y3P8
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_014450
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_055265
Curated Selection
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