SIT (SIT1) (NM_014450) Human Recombinant Protein

Product Specifications

Background

Negatively regulates TCR (T-cell antigen receptor) -mediated signaling in T-cells. Involved in positive selection of T-cells.[UniProtKB/Swiss-Prot Function]

Overview

Recombinant protein of human signaling threshold regulating transmembrane adaptor 1 (SIT1)

Synonyms

SIT; SIT-R

Gene ID

27240

UniProt

Q9Y3P8

Accession Number mRNA

NM_014450

Chromosomal Location

9p13.3

Expression System

HEK293T

Tag

C-Myc/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Transmembrane

Molecular Weight

20.9 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.