ON123300
ON123300 is a potent, multi-targeted kinase inhibitor with low nanomolar IC50 values against CDK4, Ark5, PDGFRβ, FGFR1, RET, and Fyn. It is a valuable research tool for studying cell cycle progression, oncogenic signaling, and tumor angiogenesis in both cellular and animal models of cancer.
Product Specifications
CAS Number
1357470-29-1
Product Name Alternative
CDK, CDK6, CDK4, cRET, Cyclin dependent kinase, brain, AMPK, AMP-activated protein kinase, Ark5, ON 123300, ON123300, ON-123300, multi, inhibit, kinase, Inhibitor, FGFR1, glioma, Fyn, FYN, RET, RTK, Platelet-derived growth factor receptor, penetration, PDGFR, PDGFRβ, U87, tumor
Field of Research
Cardiovascular Research, Cell Biology, Epigenetics & Chromatin, Signal Transduction, Stem Cell & Developmental Biology
Purity
99.22% (May vary between batches)
Solubility
H2O:< 1 mg/mL (insoluble or slightly soluble) ; DMSO:< 1 mg/mL (insoluble or slightly soluble) ; Ethanol:< 1 mg/mL (insoluble or slightly soluble)
Smiles
CN1CCN (CC1) c1ccc (Nc2ncc3cc (C#N) c (=O) n (C4CCCC4) c3n2) cc1
Molecular Formula
C24H27N7O
Molecular Weight
429.52
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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