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Sivelestat

Sivelestat (ONO5046) is a highly selective neutrophil elastase inhibitor with an IC50 of 44 nM. It is widely used in research on acute lung injury (ALI), acute respiratory distress syndrome (ARDS), and other inflammatory conditions, with applications in both in vitro and in vivo experimental models.

Product Specifications

CAS Number

127373-66-4

Product Name Alternative

ONO-5046

Field of Research

Neuroscience

Purity

>98%

Bioactivity

Leukocyte elastase inhibitor

Form

Powder

Solubility

Soluble in DMSO (up to 20 mg/ml) .

Smiles

CC (C) (C) C (=O) Oc1ccc (cc1) S (=O) (=O) Nc1ccccc1C (=O) NCC (O) =O

Molecular Formula

C20H21N2O7

Molecular Weight

456.45

Storage Conditions

RT

Notes

For research use only.

Other Product Names

N-{2-[ ({4-[ (2,2-Dimethylpropanoyl) oxy]phenyl}sulfonyl) amino]benzoyl}glycine sodium

Available Sizes

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