HC-5404
Product Specifications
CAS Number
2247396-91-2
Target
PERK
Related Pathways
Apoptosis
Purity
0.9933
Bioactivity
HC-5404 is a novel, potent and highly selective PERK (Protein kinase RNA-like Endoplasmic Reticulum Kinase) inhibitor, blocking the activation of the PERK pathway, which in turn inhibits the endoplasmic reticulum stress response signaling pathway, thereby exerting anti-tumor effects, and can be used to treat advanced solid tumors and renal cell Cancer.
Smiles
CC1=C(C=2C=C(C(NC(C)C)=O)C(N)=NC2)C=CC(NC([C@H](O)C3=CC(F)=CC(F)=C3)=O)=C1
Molecular Formula
C24H24F2N4O3
Molecular Weight
454.47
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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