GSK805
GSK805 is a potent, selective, and orally active RORγt inverse agonist with demonstrated blood-brain barrier penetration. It is a valuable research tool for investigating Th17-driven biology in both cellular assays and animal models of autoimmune and inflammatory diseases.
Product Specifications
CAS Number
1426802-50-7
Product Name Alternative
CNS penetrant, Inhibitor, inhibit, oral, immunity, GSK805, GSK-805, GSK 805, ROR, RORγt, Th17 cell, RAR-related orphan receptor
Field of Research
Metabolism Research
Purity
≥95% (May vary between batches)
Solubility
DMSO:100 mg/mL (187.84 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:10 mg/mL (18.78 mM)
Smiles
CCS (=O) (=O) c1ccc (CC (=O) Nc2cc (Cl) c (c (Cl) c2) -c2ccccc2OC (F) (F) F) cc1
Molecular Formula
C23H18Cl2F3NO4S
Molecular Weight
532.36
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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