GSK547
GSK547 is a potent and selective RIP1 kinase inhibitor. It has been shown to block macrophage-induced adaptive immune tolerance in pancreatic cancer models, supporting its use in oncology and immunology research involving both in vitro and in vivo studies.
Product Specifications
CAS Number
2226735-55-1
Product Name Alternative
Inhibitor, inhibit, GSK 547, GSK547, GSK'547, GSK-547, Receptor-interacting protein kinases, RIP kinase, RIP1, RIPK, RIPkinase
Field of Research
Cell Biology, Signal Transduction
Purity
99.17% (May vary between batches)
Solubility
DMSO:125 mg/mL (315.35 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (10.09 mM)
Smiles
Fc1cc (F) cc (c1) [C@@H]1CC=NN1C (=O) C1CCN (CC1) c1cc (ncn1) C#N
Molecular Formula
C20H18F2N6O
Molecular Weight
396.39
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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