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5’-Deoxy-5’-N, N-diethylamino thymidine

5’-Deoxy-5’-N, N-diethylamino thymidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Product Specifications

CAS Number

[2305415-88-5]

UNSPSC

12352005

Target

Nucleoside Antimetabolite/Analog

Type

Oligonucleotides

Related Pathways

Cell Cycle/DNA Damage

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/5-deoxy-5-n-n-diethylamino-thymidine.html

Solubility

10 mM in DMSO

Smiles

O=C(NC(C(C)=C1)=O)N1[C@@H]2O[C@H](CN(CC)CC)[C@@H](O)C2

Molecular Formula

C14H23N3O4

Molecular Weight

297.35

References & Citations

[1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18 (23) :3373-88.

Shipping Conditions

Room temperature

Scientific Category

Oligonucleotides

Clinical Information

No Development Reported

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