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BIX-01294

BIX-01294 is a cell-permeable, potent, and selective inhibitor of the histone methyltransferase G9a (IC50 = 1.9 μM) . It is widely used in epigenetic research to probe the role of histone H3 lysine 9 methylation in gene silencing, cellular differentiation, and has demonstrated utility in both in vitro and in vivo experimental models.

Product Specifications

CAS Number

935693-62-2

Product Name Alternative

PRMT1, recurrent, p21, SUV39H1 (H320R), inhibit, Inhibitor, MLKL, p53, Histone Methyltransferase, HistoneMethyltransferase, Gadd45a, G9a, H3K9me2, H3K9me3, Cdkn1a, Autophagy, BIX 01294, BIX01294, BIX-01294

Field of Research

Epigenetics & Chromatin, Neuroscience, Stem Cell & Developmental Biology

Purity

>98%

Bioactivity

Histone methyl transferase inhibitor

Form

Powder

Solubility

Soluble in DMSO (up to 50 mg/ml), or in Water (up to 50 mg/ml) .

Smiles

N (C=1C2=C (N=C (N1) N3CCN (C) CCC3) C=C (OC) C (OC) =C2) C4CCN (CC5=CC=CC=C5) CC4

Molecular Formula

C28H38N6O2 • 3HCl

Molecular Weight

600.0

Storage Conditions

RT

Notes

For research use only.

Other Product Names

2- (Hexahydro-4-methyl-1H-1,4-diazepin-1-yl) -6,7-dimethoxy-N-[1- (phenylmethyl) -4-piperidinyl]-4-quinazolinamine, trihydrochloride

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